Optimizing Nasal Interface for Continuous Positive Airway Pressure in Neonates.

Nasal continuous positive airway pressure (CPAP) as the primary mode of respiratory support in preterm neonates with respiratory distress is associated with reduced needs of surfactant therapy and invasive ventilation, and improved survival without bronchopulmonary dysplasia [1,2]. Despite convincing evidence of benefits, use and success rate of CPAP remain variable across different neonatal units. Major challenges in CPAP application in routine clinical practice include ensuring proper fixation and avoiding nasal injury.